Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 7/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 9/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437663 | 0.88 | MDM2 (0.42) | AVPR1BMERTKMDM2MMP13CNR1 | |
| SCHEMBL21438114 | 0.87 | ACACB (0.43) | — | |
| SCHEMBL21437211 | 0.82 | MDM2 (0.42) | AVPR1BMDM2MMP13MMP3 | |
| SCHEMBL21437212 | 0.81 | AVPR1B (0.37) | AVPR1BMERTKMDM2MMP13MMP3 | |
| SCHEMBL21455901 | 0.76 | MDM2 (0.45) | MDM2 | |
| SCHEMBL21437980 | 0.75 | ACACB (0.43) | MDM2 | |
| SCHEMBL21455903 | 0.74 | BRD4 (0.41) | MDM2 | |
| SCHEMBL21437626 | 0.73 | BRD4 (0.41) | MDM2 | |
| SCHEMBL21437634 | 0.72 | CFD (0.54) | — | |
| SCHEMBL21438902 | 0.71 | AOC3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112272553-A | Substituted benzofurans, benzopyrrole, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2021-01-26 | — | — | CN | disclosed |
| EP-3687506-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |