Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174593 | 0.90 | ALOX5 (0.43) | NFE2L2ALOX5KDM1AHDAC1HDAC6 | |
| SCHEMBL3287495 | 0.79 | ALOX5 (0.49) | ALOX5HDAC6RELAHPGDSMN1; SMN2 | |
| SCHEMBL23555385 | 0.79 | ALOX5 (0.47) | ALOX5HDAC6HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL16174592 | 0.79 | ALOX5 (0.45) | ALOX5HDAC6 | |
| SCHEMBL23555387 | 0.78 | ALOX5 (0.46) | ALOX5HDAC6HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL14802125 | 0.74 | ALOX5 (0.40) | ALOX5HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL22173936 | 0.73 | KDM1A (0.31) | ALOX5KDM1AHDAC1HDAC6 | |
| SCHEMBL10985315 | 0.72 | ALOX5 (0.53) | ALOX5HDAC6HPGDPTGS2 | |
| SCHEMBL17474342 | 0.72 | ALOX5 (0.58) | ALOX5HDAC6HPGDKDM4EPTGS1 | |
| SCHEMBL16166718 | 0.71 | ALOX5 (0.41) | ALOX5HDAC6HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | NAT1, SLCO2A1, SLCO2B1 | NFE2L2 564/4885ALOX5 445/4885KDM1A 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.