SCHEMBL2144063

SCHEMBL2144063

CCCCCC[Si](CCCCCC)(CCCCCC)C(CCCCC)OC(=O)/C=C/C(=O)OC(CCCCC)[Si](CCCCCC)(CCCCCC)CCCCCC

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.39
ATM Q13315 1/20 0.38
GPR84 Q9NQS5 7/20 0.37
FFAR1 O14842 1/20 0.37
ZDHHC7 Q9NXF8 1/20 0.37
LMNA P02545 3/20 0.36
MAPT P10636 1/20 0.36
LCK P06239 1/20 0.36
PPARD Q03181 1/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
FAAH O00519 2/20 0.36
CA2 P00918 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2144510 0.95 ATM (0.39) HCAR2ATMLMNAZDHHC20ZDHHC2
SCHEMBL2144575 0.87 ATM (0.40) HCAR2ATMLMNAMAPTZDHHC20
SCHEMBL5838908 0.87 ATM (0.40) HCAR2ATMLMNAMAPTZDHHC20
SCHEMBL29382241 0.76 FAAH (0.54) HCAR2ATMGPR84FFAR1LMNA
SCHEMBL10385574 0.75 HCAR2 (0.50) HCAR2ATMGPR84FFAR1ZDHHC7
SCHEMBL10897489 0.75 HCAR2 (0.50) HCAR2ATMGPR84FFAR1ZDHHC7
SCHEMBL10387539 0.75 HCAR2 (0.50) HCAR2ATMGPR84FFAR1ZDHHC7
SCHEMBL2831197 0.75 HCAR2 (0.50) HCAR2ATMGPR84FFAR1ZDHHC7
SCHEMBL2833618 0.75 HCAR2 (0.50) HCAR2ATMGPR84FFAR1ZDHHC7
SCHEMBL18209639 0.75 HCAR2 (0.50) HCAR2ATMGPR84FFAR1ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed