Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.67 |
| ▸ | WNT3A | P56704 | 7/20 | 0.67 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441417 | 0.88 | CTNNB1 (0.55) | CTNNB1WNT3AMETTL3KDM4EALDH1A1 | |
| SCHEMBL21441262 | 0.87 | CTNNB1 (0.66) | CTNNB1WNT3AALDH1A1MAPTROCK2 | |
| SCHEMBL21441367 | 0.86 | CTNNB1 (0.67) | CTNNB1WNT3ANOS1KDM4EALDH1A1 | |
| SCHEMBL21441341 | 0.86 | CLK1 (0.51) | CTNNB1WNT3ANOS1KDM4EALDH1A1 | |
| SCHEMBL21441407 | 0.83 | CTNNB1 (0.50) | CTNNB1WNT3ANOS1KDM4EALDH1A1 | |
| SCHEMBL21441278 | 0.83 | CTNNB1 (0.51) | CTNNB1WNT3ARAB9ATRPA1 | |
| SCHEMBL21441419 | 0.82 | CTNNB1 (0.50) | CTNNB1WNT3AROCK2ROCK1METAP2 | |
| SCHEMBL21441403 | 0.82 | CTNNB1 (0.49) | CTNNB1WNT3ANOS1KDM4EALDH1A1 | |
| SCHEMBL21441365 | 0.81 | CTNNB1 (0.54) | CTNNB1WNT3ANOS1KDM4EALDH1A1 | |
| SCHEMBL15969687 | 0.80 | CTNNB1 (1.00) | CTNNB1WNT3AMETTL3CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |