Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.54 |
| ▸ | WNT3A | P56704 | 7/20 | 0.54 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441274 | 0.86 | CTNNB1 (0.67) | CTNNB1WNT3ACLK1DYRK3CLK2 | |
| SCHEMBL21441262 | 0.85 | CTNNB1 (0.66) | CTNNB1WNT3ACLK1DYRK3CLK2 | |
| SCHEMBL21441341 | 0.83 | CLK1 (0.51) | CTNNB1WNT3ACLK1DYRK3CLK2 | |
| SCHEMBL21441359 | 0.83 | CTNNB1 (0.48) | CTNNB1WNT3ACLK1CLK2DYRK1A | |
| SCHEMBL21441408 | 0.83 | CTNNB1 (0.51) | CTNNB1WNT3ADYRK3CLK2DYRK1A | |
| SCHEMBL21441401 | 0.83 | CTNNB1 (0.53) | CTNNB1WNT3ACLK1DYRK3CLK2 | |
| SCHEMBL21441403 | 0.82 | CTNNB1 (0.49) | CTNNB1WNT3ACLK1DYRK3CLK2 | |
| SCHEMBL21441407 | 0.81 | CTNNB1 (0.50) | CTNNB1WNT3ACLK1DYRK3CLK2 | |
| SCHEMBL21441367 | 0.81 | CTNNB1 (0.67) | CTNNB1WNT3ADYRK3CLK2GSK3B | |
| SCHEMBL21441263 | 0.81 | CTNNB1 (0.67) | CTNNB1WNT3ANOS1RAB9ACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |