Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21716289 | 0.89 | TRPA1 (0.78) | TRPA1ATM | |
| SCHEMBL18018197 | 0.89 | TRPA1 (0.82) | TRPA1 | |
| SCHEMBL16648077 | 0.89 | TRPA1 (0.79) | TRPA1 | |
| SCHEMBL18017576 | 0.85 | TRPA1 (0.82) | TRPA1 | |
| SCHEMBL16648243 | 0.84 | TRPA1 (0.77) | TRPA1 | |
| SCHEMBL20113258 | 0.83 | TRPA1 (0.78) | TRPA1 | |
| SCHEMBL18017805 | 0.83 | TRPA1 (0.77) | TRPA1ATM | |
| SCHEMBL16648126 | 0.81 | TRPA1 (0.79) | TRPA1ATM | |
| SCHEMBL16648093 | 0.81 | TRPA1 (0.78) | TRPA1 | |
| SCHEMBL18018379 | 0.81 | TRPA1 (0.76) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256463-B1 | 1-(HET)ARYLSULFONYL-(PYRROLIDINE OR PIPERIDINE)-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2019-10-09 | — | — | EP | disclosed |