SCHEMBL214423

SCHEMBL214423

O=C1O/C(=C\c2ccccc2)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 1.00
ALDH1A1 P00352 5/20 1.00
HPGD P15428 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
CYP1A2 P05177 2/20 0.73
CYP2C19 P33261 2/20 0.73
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
POLB P06746 1/20 0.73
CYP3A4 P08684 1/20 0.73
CYP2C9 P11712 1/20 0.73
NFKB1 P19838 1/20 0.73
NFKB2 Q00653 1/20 0.73
RELA Q04206 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
STK17B O94768 1/20 0.59
TSHR P16473 1/20 0.53
MAPK1 P28482 1/20 0.53
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5433929 1.00 KDM4E (1.00) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL29637244 1.00 KDM4E (1.00) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL214424 1.00 KDM4E (1.00) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL11776868 0.88 KDM4E (0.79) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL11776872 0.88 KDM4E (0.79) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL10385009 0.86 KDM4E (0.75) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL10384911 0.86 KDM4E (0.75) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL10384913 0.86 KDM4E (0.75) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL10384258 0.86 KDM4E (0.75) KDM4EALDH1A1HPGDTDP1L3MBTL1
SCHEMBL8145721 0.85 KDM4E (0.73) KDM4EALDH1A1HPGDTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 475 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170190145-A1 SURFBOARD WAX WITH SUNSCREEN BALLENAS RYAN CHARLES (US) 2017-07-06 US claimed
EP-2293761-B1 COMPOSITIONS FOR TOPICAL APPLICATION COMPRISING MICROENCAPSULATED COLORANTS TAGRA BIOTECHNOLOGIES LTD (IL) 2017-02-01 EP claimed
EP-2575750-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE International Flora Technologies, Ltd. (US) 2013-04-10 EP claimed
WO-2011149929-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-12-01 WO claimed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 US claimed
US-20110229536-A1 COMPOSITIONS FOR TOPICAL APPLICATION COMPRISING MICROENCAPSULATED COLORANTS TAGRA BIOTECHNOLOGIES LTD. (IL) 2011-09-22 US claimed
EP-2293761-A2 COMPOSITIONS FOR TOPICAL APPLICATION COMPRISING MICROENCAPSULATED COLORANTS Tagra Biotechnologies Ltd (IL) 2011-03-16 EP claimed
WO-2009138978-A2 COMPOSITIONS FOR TOPICAL APPLICATION COMPRISING MICROENCAPSULATED COLORANTS TAGRA BIOTECHNOLOGIES LTD (IL) 2009-11-19 WO claimed
US-5424263-A Product formed by contacting silica with hydrocarbon-soluble magnesium compound, heterocyclic fused ring compound having oxygen substituent, modifying silicon, boron or aluminum halide, titanium compound QUANTUM CHEMICAL CORPORATION (US) 1995-06-13 US claimed
WO-1994025156-A1 SUPPORTED POLYMERIZATION CATALYST QUANTUM CHEMICAL CORPORATION (US) 1994-11-10 WO claimed
US-4710371-A BUTENE POLYMER AND ULTRAVIOLET RADIATION ABSORBER PALINCZAR VICTOR (US) 1987-12-01 US claimed
US-4699779-A Waterproof sunscreen compositions PALINCZAR VICTOR 1987-10-13 US claimed
EP-0232734-A1 Use of 3-benzalphthalides as UV stabilizers for thermoplastic, aromatic polyesters, polycarbonates and polyester carbonates BAYER AG (DE) 1987-08-19 EP claimed
US-4686099-A Aerosol waterproof sunscreen compositions CHESEBROUGH-POND'S INC. 1987-08-11 US claimed
US-4683134-A HIGH VISCOSITY, GELS, ETHYL CELLULOSE, CROSSLINKED POLYACRYLIC ACID PALINCZAR VICTOR 1987-07-28 US claimed
EP-0105131-B1 2-(OMEGA-ALKYLAMINOALKYL)- AND 2-(OMEGA-DIALKYLAMINOALKYL)-3-(4-X-BENZYLIDENE)-PHTHALIMIDINES LABORATORI BALDACCI Spa (IT) 1987-03-11 EP claimed
US-4457911-A Dialkyl malonates as organic sunscreen adjuvants VAN DYK & COMPANY INC. (US) 1984-07-03 US claimed
EP-0100651-A1 Dialkyl malonates as organic suncreen adjuvants VAN DYK & COMPANY, INC. (US) 1984-02-15 EP claimed
US-4333920-A Benzalphthalides and broad spectrum sun screens VAN DYK & COMPANY, INC. (US) 1982-06-08 US claimed
US-4199021-A Thermal energy storage apparatus JOHNSON CONTROLS, INC. (US) 1980-04-22 US claimed