⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22385235 | 0.80 | LMNA (0.33) | — | |
| SCHEMBL10899960 | 0.80 | — | — | |
| SCHEMBL2058394 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL10858369 | 0.76 | CYP1A2 (0.46) | — | |
| SCHEMBL4079032 | 0.76 | — | — | |
| SCHEMBL5078372 | 0.76 | — | — | |
| SCHEMBL19696277 | 0.76 | LMNA (0.38) | — | |
| SCHEMBL11048426 | 0.76 | — | — | |
| SCHEMBL9427113 | 0.76 | MEN1 (0.42) | — | |
| SCHEMBL11048013 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3231798-B1 | THIAZOLE INTERMEDIATES USEFUL IN THE PREPARATION OF RAF KINASE INHIBITORS | SUNESIS PHARMACEUTICALS INC (US) | 2019-10-09 | — | — | EP | disclosed |