Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 19/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15724912 | 0.82 | TSHR (0.51) | GLSTSHR | |
| SCHEMBL14987651 | 0.82 | RECQL (0.76) | GLSTSHR | |
| SCHEMBL14987158 | 0.79 | GLS (1.00) | GLS | |
| SCHEMBL15042300 | 0.79 | GLS (0.73) | GLSTSHR | |
| SCHEMBL14986989 | 0.79 | GLS (1.00) | GLS | |
| SCHEMBL14987534 | 0.78 | GLS (1.00) | GLSTSHR | |
| SCHEMBL21443484 | 0.77 | GLS (0.73) | GLS | |
| SCHEMBL15042287 | 0.77 | GLS (0.70) | GLSTSHR | |
| SCHEMBL21443384 | 0.76 | GLS (0.71) | GLS | |
| SCHEMBL18122469 | 0.76 | GLS (0.70) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922832-B1 | GLUTAMINASE INHIBITORS AND METHODS OF USE | AGIOS PHARMACEUTICALS INC (US) | 2019-10-09 | — | — | EP | disclosed |