Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248954 | 0.93 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4MEN1 | |
| SCHEMBL5335092 | 0.86 | NOTUM (0.40) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL29627844 | 0.86 | NOTUM (0.40) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL4206469 | 0.80 | BCHE (0.39) | GRIA1GRIA2GRIA3GRIA4MEN1 | |
| SCHEMBL27707619 | 0.75 | GRIA1 (0.37) | GRIA1GRIA2GRIA3GRIA4TSHR | |
| SCHEMBL9267430 | 0.74 | PARP1 (0.42) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL19249411 | 0.73 | BCL2L1 (0.48) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL6221804 | 0.73 | PARP1 (0.44) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL31170775 | 0.73 | PARP1 (0.44) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL31170771 | 0.72 | NOTUM (0.44) | GRIA1GRIA2GRIA3GRIA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2811993-B1 | METHODS OF TREATING FIBROSIS | NOGRA PHARMA LTD (IE) | 2019-10-09 | — | — | EP | disclosed |