Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248954 | 0.81 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4NUDT1 | |
| SCHEMBL5542226 | 0.77 | NOTUM (0.40) | BCHEPARP1PARP10PARP11 | |
| SCHEMBL5757236 | 0.76 | NUDT1 (0.47) | GRIA1GRIA2GRIA3GRIA4NUDT1 | |
| SCHEMBL30826409 | 0.76 | NUDT1 (0.47) | GRIA1GRIA2GRIA3GRIA4NUDT1 | |
| SCHEMBL21443855 | 0.75 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4NUDT1 | |
| SCHEMBL8364082 | 0.71 | NOTUM (0.43) | BCHEPARP1TP53PARP10PARP11 | |
| SCHEMBL27707696 | 0.71 | MEN1 (0.34) | CYP1A2RAB9A | |
| SCHEMBL4206469 | 0.71 | BCHE (0.39) | GRIA1GRIA2GRIA3GRIA4NUDT1 | |
| SCHEMBL31170775 | 0.71 | PARP1 (0.44) | GRIA1GRIA2GRIA3GRIA4NUDT1 | |
| SCHEMBL6221804 | 0.71 | PARP1 (0.44) | GRIA1GRIA2GRIA3GRIA4NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048414-B | Fused tricyclic derivatives for the treatment of psychotic disorders | GLAXO GROUP LTD | 2011-09-07 | — | — | CN | disclosed |
| CN-101048414-A | Fused tricyclic derivatives for the treatment of psychotic disorders | GLAXO GROUP LTD (GB) | 2007-10-03 | — | — | CN | disclosed |