SCHEMBL2144409

SCHEMBL2144409

CCC[Si](CCC)(CCC)C(CC)OC(=O)/C=C/C(=O)OC(CC)[Si](CCC)(CCC)CCC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.35
ATM Q13315 1/20 0.35
TSHR P16473 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7221819 0.85 TSHR (0.39) TSHR
SCHEMBL8733393 0.78 HCAR2 (0.39) HCAR2ATMTSHRKEAP1NFE2L2
SCHEMBL3482632 0.78 HCAR2 (0.39) HCAR2ATMTSHRKEAP1NFE2L2
SCHEMBL2144575 0.77 ATM (0.40) HCAR2ATMTSHR
SCHEMBL5838908 0.77 ATM (0.40) HCAR2ATMTSHR
SCHEMBL11322959 0.76 HCAR2 (0.38) HCAR2ATMKEAP1NFE2L2
SCHEMBL11322949 0.76 HCAR2 (0.38) HCAR2ATMKEAP1NFE2L2
SCHEMBL2144510 0.75 ATM (0.39) HCAR2ATMTSHR
SCHEMBL4312022 0.74 HCAR2 (0.36) HCAR2ATMKEAP1NFE2L2
SCHEMBL4312008 0.74 HCAR2 (0.36) HCAR2ATMKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed