Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18811652 | 0.96 | MEN1 (0.55) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL20748813 | 0.96 | MEN1 (0.55) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL21323141 | 0.89 | MEN1 (0.50) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL27771651 | 0.89 | MEN1 (0.52) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL31407660 | 0.89 | MEN1 (0.52) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL29581953 | 0.87 | MEN1 (0.52) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL29576686 | 0.87 | MEN1 (0.52) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL29503454 | 0.86 | SLC6A5 (0.48) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL18811650 | 0.85 | MEN1 (0.47) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL29964588 | 0.85 | MEN1 (0.56) | MEN1KMT2AGAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134125-B1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2019-10-09 | — | — | EP | disclosed |