SCHEMBL21445215

SCHEMBL21445215

CC(C)(C)OC(=O)N1CCN(CC(O)CN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 19/20 0.72
RAD52 P43351 2/20 0.51
NPC1 O15118 1/20 0.51
MLNR O43193 1/20 0.51
USP1 O94782 1/20 0.51
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
ESR1 P03372 1/20 0.51
TP53 P04637 1/20 0.51
CYP1A2 P05177 1/20 0.51
ABCB1 P08183 1/20 0.51
CYP3A4 P08684 1/20 0.51
HTR1A P08908 1/20 0.51
ADRA2A P08913 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
CALM1 P0DP23 1/20 0.51
CYP2D6 P10635 1/20 0.51
MAPT P10636 1/20 0.51
CHRM1 P11229 1/20 0.51
DRD2 P14416 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23039437 1.00 FPR2 (0.72) FPR2RAD52NPC1MLNRUSP1
SCHEMBL30056330 1.00 FPR2 (0.72) FPR2RAD52NPC1MLNRUSP1
SCHEMBL21445258 0.90 FPR2 (0.72) FPR2RAD52NPC1MLNRUSP1
SCHEMBL14809970 0.89 FPR2 (0.61) FPR2RAD52
SCHEMBL23039426 0.87 FPR2 (0.78) FPR2RAD52LMNATP53CYP1A2
SCHEMBL21445213 0.86 FPR2 (0.71) FPR2RAD52NPC1MLNRUSP1
SCHEMBL30534415 0.86 FPR2 (0.71) FPR2RAD52NPC1MLNRUSP1
SCHEMBL21445260 0.84 FPR2 (1.00) FPR2RAD52NPC1MLNRUSP1
SCHEMBL21445229 0.83 FPR2 (0.78) FPR2RAD52
SCHEMBL21445267 0.83 FPR2 (0.79) FPR2RAD52LMNATP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034193-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2025-01-30 US disclosed
US-12145963-B2 Phenothiazine derivatives and uses thereof CAMP4 THERAPEUTICS CORPORATION (US) 2024-11-19 US disclosed
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2023-08-17 US disclosed
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2023-08-17 US disclosed
US-11542290-B2 Phenothiazine derivatives and uses thereof CAMP4 THERAPEUTICS CORPORATION (US) 2023-01-03 US disclosed
US-11542290-B2 Phenothiazine derivatives and uses thereof CAMP4 THERAPEUTICS CORPORATION (US) 2023-01-03 US disclosed
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2021-03-04 US disclosed
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2021-03-04 US disclosed
WO-2019195789-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION (US) 2019-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885RAD52 1387/4885NPC1 2869/4885
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885RAD52 1387/4885NPC1 2869/4885
US-12145963-B2 Phenothiazine derivatives and uses thereof RPLP2, RPS2, RPLP1 FPR2 2716/4885RAD52 1387/4885NPC1 2869/4885
US-20250034193-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885RAD52 1387/4885NPC1 2869/4885
US-11542290-B2 Phenothiazine derivatives and uses thereof RPLP2, RPS2, RPLP1 FPR2 2716/4885RAD52 1387/4885NPC1 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.