SCHEMBL21445238

SCHEMBL21445238

NSNCC1CCN(CC(O)CN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 18/20 0.77
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21445231 0.91 FPR2 (0.75) FPR2MEN1KMT2A
SCHEMBL21445232 0.87 FPR2 (0.76) FPR2MEN1KMT2A
SCHEMBL30534412 0.87 FPR2 (0.76) FPR2MEN1KMT2A
SCHEMBL26002224 0.87 FPR2 (0.76) FPR2MEN1KMT2A
SCHEMBL21445202 0.87 FPR2 (1.00) FPR2MEN1KMT2A
SCHEMBL21445282 0.86 FPR2 (0.75) FPR2MEN1KMT2A
SCHEMBL21445203 0.86 FPR2 (1.00) FPR2MEN1KMT2A
SCHEMBL23039409 0.86 FPR2 (0.86) FPR2MEN1KMT2A
SCHEMBL21445204 0.85 FPR2 (0.85) FPR2MEN1KMT2A
SCHEMBL26000540 0.83 FPR2 (0.72) FPR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019195789-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION (US) 2019-10-10 WO disclosed