SCHEMBL21446409

SCHEMBL21446409

CC1(C)c2ccccc2-c2c(Nc3cccc4c3C(C)(C)c3ccccc3-4)cccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.40
MLNR O43193 1/20 0.33
NR1I2 O75469 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRB1 P08588 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
CHRM3 P20309 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637475 0.92 PDK2 (0.45) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL29771223 0.92 PDK2 (0.45) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL23658594 0.90 PDK2 (0.37) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL18647780 0.87 PDK2 (0.40) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL21615066 0.83 PDK2 (0.35) PDK2MAPTMAPK1RAB9ASMN1; SMN2
SCHEMBL20182308 0.83 MAPT (0.42) PDK2EGFRMAPTMAPK1SMN1; SMN2
SCHEMBL15840198 0.83 PDK2 (0.39) PDK2PGRMAPT
SCHEMBL17777676 0.83 FABP4 (0.44) PDK2SMN1; SMN2
SCHEMBL15250325 0.83 PDK2 (0.42) PDK2PGRMAPTSMN1; SMN2
SCHEMBL29598725 0.83 FABP4 (0.44) PDK2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021145651-A1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-22 WO disclosed
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed
WO-2019192954-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-10-10 WO disclosed