SCHEMBL2144676

SCHEMBL2144676

[CH2]CCCC[Si](CCCCC)(CCCCC)CCCCC

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
THRB P10828 1/20 0.37
LMNA P02545 1/20 0.32
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2144180 0.97 TSHR (0.42) TSHRTHRBLMNASLC22A1
SCHEMBL2144210 0.97 TSHR (0.42) TSHRTHRBLMNASLC22A1
SCHEMBL686671 0.86
SCHEMBL16344126 0.86 TSHR (0.42) TSHRTHRBLMNASLC22A1
SCHEMBL2144498 0.86 TSHR (0.33) TSHRTHRBLMNA
SCHEMBL562896 0.85 TSHR (0.50) TSHRTHRBLMNASLC22A1SLC22A2
SCHEMBL2124312 0.82 TSHR (0.57) TSHRTHRBLMNASLC22A1
SCHEMBL10401825 0.82 TSHR (0.57) TSHRTHRBLMNASLC22A1
SCHEMBL10841725 0.82 TSHR (0.57) TSHRTHRBLMNASLC22A1
SCHEMBL16209877 0.82 TSHR (0.57) TSHRTHRBLMNASLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed