SCHEMBL562896

SCHEMBL562896

CCCCC[Si](CCCCC)(CCCCC)CCCCC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 3/20 0.43
SLC22A1 O15245 3/20 0.39
SLC22A2 O15244 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
DNM1 Q05193 5/20 0.37
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120007 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL1937969 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL2119967 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL10401825 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL7849811 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL2124312 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL16209877 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL1329750 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL10841183 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL10841725 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112823172-A Resin composition 库比科有限责任公司 2021-05-18 CN claimed
US-11312633-B2 Silicon-carbon composite powder EVONIK OPERATIONS GMBH (DE) 2022-04-26 US disclosed
CN-112823172-A Resin composition 库比科有限责任公司 2021-05-18 CN disclosed
EP-1550683-B1 POLYESTER RESIN COMPOSITIONS, POLYESTER FILM, AND MAGNETIC RECORDING MEDIUM TORAY INDUSTRIES (JP) 2017-04-26 EP disclosed
US-9405885-B2 Drug discovery method Keddem Bioscience Ltd. (IL) 2016-08-02 US disclosed
US-9405885-B2 Drug discovery method Keddem Bioscience Ltd. (IL) 2016-08-02 US disclosed
US-20130072647-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2013-03-21 US disclosed
EP-2567986-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2013-03-13 EP disclosed
US-20130059818-A1 CARBOSILANE DENDRIMERS AND THE USE THEREOF AS ANTIVIRAL AGENTS UNIVERSIDAD DE ALCALA DE HENARES (UAH) (ES) 2013-03-07 US disclosed
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition SAKAMOTO JUN (JP) 2012-02-09 US disclosed
US-20110237458-A1 DRUG DISCOVERY METHOD Keddem Bioscience Ltd. (IL) 2011-09-29 US disclosed
US-20100209735-A1 Polyester resin compositions, polyester film, and magnetic recording medium YOSHIMURA HITOSHI 2010-08-19 US disclosed
US-7709594-B2 Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium TORAY INDUSTRIES, INC. (JP) 2010-05-04 US disclosed
US-20050239929-A1 Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium TORAY INDUSTRIES, INC. (JP) 2005-10-27 US disclosed
EP-1550683-A1 POLYESTER RESIN COMPOSITIONS, CATALYST FOR POLYESTER PRODUCTION, POLYESTER FILM, AND MAGNETIC RECORDING MEDIUM TORAY INDUSTRIES, INC. (JP) 2005-07-06 EP disclosed
US-4307156-A PROTECTIVE COATINGS OF POLYSILICATES OVER INTERMEDIATE LAYER OF A METAL OXIDE OR PHOSPHATE NIPPON ELECTRIC CO., LTD. (JP) 1981-12-22 US disclosed
US-4152487-A ALLOYS, POLYSILICATES NIPPON ELECTRIC CO., LTD. (JP) 1979-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059818-A1 CARBOSILANE DENDRIMERS AND THE USE THEREOF AS ANTIVIRAL AGENTS POLI, PCNA, PICALM TSHR 4691/4885THRB 4862/4885LMNA 3940/4885
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition PUF60, RPS24, SRP54 TSHR 870/4885THRB 1519/4885LMNA 4813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.