Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072372 | 0.86 | ALDH1A1 (0.61) | TSHRALDH1A1CETPLMNAALPG | |
| SCHEMBL27908642 | 0.83 | TSHR (1.00) | TSHRALDH1A1SRCCETPLMNA | |
| SCHEMBL51316 | 0.83 | TSHR (1.00) | TSHRALDH1A1SRCCETPLMNA | |
| SCHEMBL4219700 | 0.81 | TSHR (0.96) | TSHRALDH1A1SRCCETPLMNA | |
| Hydrochloric Acid SCHEMBL10722992 | 0.81 | TSHR (0.96) | TSHRALDH1A1SRCCETPLMNA | |
| Ammonia Solution, Strong SCHEMBL7268743 | 0.81 | TSHR (0.96) | TSHRALDH1A1SRCCETPLMNA | |
| SCHEMBL11756554 | 0.81 | TSHR (0.96) | TSHRALDH1A1SRCCETPLMNA | |
| Phosphoric Acid SCHEMBL27741297 | 0.81 | TSHR (0.96) | TSHRALDH1A1SRCCETPLMNA | |
| SCHEMBL9446520 | 0.81 | TSHR (0.96) | TSHRALDH1A1SRCCETPLMNA | |
| SCHEMBL28032525 | 0.81 | TSHR (0.96) | TSHRALDH1A1SRCCETPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195159-A1 | PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2019-10-10 | — | — | WO | disclosed |