SCHEMBL21448628

SCHEMBL21448628

c1ccc2c(c1)c1ccccc1n2C1CCCCCCCC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 1/20 0.53
NPSR1 Q6W5P4 2/20 0.48
POLB P06746 1/20 0.48
TMEM97 Q5BJF2 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
GAA P10253 1/20 0.46
ALOX15 P16050 1/20 0.46
TP53 P04637 1/20 0.45
CRHBP P24387 3/20 0.44
CRHR2 Q13324 3/20 0.44
RXFP1 Q9HBX9 1/20 0.44
KDM4E B2RXH2 2/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
LMNA P02545 1/20 0.43
XBP1 P17861 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728728 1.00 MEN1 (0.53) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL31469390 1.00 MEN1 (0.53) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL21448630 1.00 MEN1 (0.53) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL21448631 1.00 MEN1 (0.53) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL31469424 0.98 MEN1 (0.50) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL524763 0.93 MEN1 (0.50) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL30417189 0.93 MEN1 (0.50) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL31469456 0.93 MEN1 (0.50) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL6947406 0.92 ALDH1A1 (0.48) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL31469417 0.89 CYP1A2 (0.48) MEN1KMT2AALDH1A1NPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10858533-B2 Anti-reflective hardmask composition Choi, Sang Jun (KR) 2020-12-08 US disclosed
US-20190309183-A1 ANTI-REFLECTIVE HARDMASK COMPOSITION CHOI, SANG JUN (KR) 2019-10-10 US disclosed