Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 15/20 | 0.76 |
| ▸ | P2RY2 | P41231 | 16/20 | 0.63 |
| ▸ | P2RY4 | P51582 | 12/20 | 0.63 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308867 | 1.00 | P2RY6 (0.76) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL15279691 | 1.00 | P2RY6 (0.76) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL15276355 | 1.00 | P2RY6 (0.76) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL19998464 | 0.98 | P2RY6 (0.73) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL20003863 | 0.98 | P2RY6 (0.73) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL19998422 | 0.92 | P2RY6 (0.64) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL20004063 | 0.92 | P2RY6 (0.64) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL20013439 | 0.92 | P2RY6 (0.68) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL21665347 | 0.92 | P2RY6 (0.68) | P2RY6P2RY2P2RY4NT5E | |
| SCHEMBL15279688 | 0.91 | P2RY6 (0.73) | P2RY6P2RY2P2RY4NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241450-B2 | Uridine diphosphate derivatives, prodrugs, compositions and uses thereof | TUFTS UNIVERSITY (US) | 2022-02-08 | — | — | US | disclosed |
| WO-2021194959-A1 | TREATMENT OF EYE DISORDERS WITH URIDINE PHOSPHATE DERIVATIVES | GLIAGUARD, INC. (US) | 2021-09-30 | — | — | WO | disclosed |
| US-11072627-B2 | Uridine diphosphate derivatives, compositions and methods for treating neurodegenerative disorders | TUFTS UNIVERSITY (US) | 2021-07-27 | — | — | US | disclosed |
| US-20210069226-A1 | URIDINE DIPHOSPHATE DERIVATIVES, PRODRUGS, COMPOSITIONS AND USES THEREOF | TUFTS UNIVERSITY (US) | 2021-03-11 | — | — | US | disclosed |
| US-20190309009-A1 | URIDINE DIPHOSPHATE DERIVATIVES, COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | TUFTS UNIVERSITY | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190309009-A1 | URIDINE DIPHOSPHATE DERIVATIVES, COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | P2RY6, P2RX6, P2RY1 | P2RY6 1/4885P2RY2 5/4885P2RY4 4/4885 |
| US-20210069226-A1 | URIDINE DIPHOSPHATE DERIVATIVES, PRODRUGS, COMPOSITIONS AND USES THEREOF | UMPS, UPP1, UGDH | P2RY6 16/4885P2RY2 53/4885P2RY4 33/4885 |
| US-11241450-B2 | Uridine diphosphate derivatives, prodrugs, compositions and uses thereof | UMPS, UPP1, UGDH | P2RY6 16/4885P2RY2 53/4885P2RY4 33/4885 |
| US-11072627-B2 | Uridine diphosphate derivatives, compositions and methods for treating neurodegenerative disorders | P2RY6, P2RX6, P2RY1 | P2RY6 1/4885P2RY2 5/4885P2RY4 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.