Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16424839 | 0.97 | CA1 (0.52) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL31726507 | 0.94 | CA1 (0.50) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL18819662 | 0.89 | CA2 (0.51) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL18831956 | 0.89 | CA2 (0.51) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL22952255 | 0.88 | CA1 (0.49) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL16862492 | 0.87 | CA1 (0.50) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL19776121 | 0.87 | CA1 (0.50) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL31121268 | 0.87 | CA1 (0.44) | CA2CA1MMP1MMP3MMP9 | |
| SCHEMBL22315797 | 0.86 | NPY4R (0.38) | SIRT1 | |
| SCHEMBL20739105 | 0.86 | NPY4R (0.38) | SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195665-A1 | CAMPTOTHECIN PEPTIDE CONJUGATES | SEATTLE GENETICS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |