Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21437366 | 0.99 | BACE1 (0.53) | BACE1EHMT2EHMT1NUDT1NPC1 | |
| SCHEMBL26451919 | 0.94 | BACE1 (0.50) | BACE1EHMT2EHMT1NUDT1NPC1 | |
| SCHEMBL22919755 | 0.89 | EHMT2 (0.54) | BACE1EHMT2EHMT1NPC1RAB9A | |
| SCHEMBL21450774 | 0.89 | EHMT2 (0.53) | BACE1EHMT2EHMT1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL21437364 | 0.88 | EHMT2 (0.53) | BACE1EHMT2EHMT1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL21437388 | 0.88 | EHMT2 (0.52) | BACE1EHMT2EHMT1NPC1RAB9A | |
| SCHEMBL22919765 | 0.87 | EHMT2 (0.56) | BACE1EHMT2EHMT1NPC1RAB9A | |
| SCHEMBL26451918 | 0.86 | EHMT2 (0.52) | BACE1EHMT2EHMT1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL21437347 | 0.86 | EHMT2 (0.55) | BACE1EHMT2EHMT1NPC1RAB9A | |
| SCHEMBL21437408 | 0.86 | BACE1 (0.53) | BACE1EHMT2EHMT1NUDT1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195493-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |