Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437350 | 0.87 | EHMT2 (0.65) | EHMT2EHMT1TSSK1BHDAC1HDAC8 | |
| SCHEMBL26451963 | 0.87 | BACE1 (0.52) | BACE1EHMT2EHMT1NUDT1KMT2A | |
| Hydrochloric Acid SCHEMBL28512158 | 0.86 | EHMT2 (0.56) | EHMT2EHMT1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL21437380 | 0.86 | EHMT2 (0.58) | BACE1EHMT2EHMT1HDAC1HDAC8 | |
| SCHEMBL21450774 | 0.86 | EHMT2 (0.53) | BACE1EHMT2EHMT1HDAC1HDAC8 | |
| SCHEMBL26451964 | 0.86 | EHMT2 (0.48) | BACE1EHMT2EHMT1TSSK1BKMT2A | |
| SCHEMBL21450755 | 0.86 | BACE1 (0.54) | BACE1EHMT2EHMT1HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL21437392 | 0.86 | BACE1 (0.52) | BACE1EHMT2EHMT1NUDT1KMT2A | |
| Hydrochloric Acid SCHEMBL21437388 | 0.85 | EHMT2 (0.52) | BACE1EHMT2EHMT1HDAC1HDAC8 | |
| SCHEMBL21437313 | 0.85 | BACE1 (0.53) | BACE1EHMT2EHMT1TLR8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774740-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | Ohio State Innovation Foundation (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019195493-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |