Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 17/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | PDCD1LG2 | Q9BQ51 | 11/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451401 | 0.83 | CD274 (0.59) | CD274PDCD1TRPV1PDCD1LG2 | |
| SCHEMBL20999512 | 0.81 | CD274 (0.53) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL14845777 | 0.79 | TRPV1 (0.43) | CD274PDCD1TRPV1PDCD1LG2 | |
| SCHEMBL24107295 | 0.79 | CD274 (0.48) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL15128430 | 0.78 | PDCD1LG2 (0.43) | CD274TRPV1PDCD1LG2 | |
| SCHEMBL10233300 | 0.72 | CD274 (0.48) | CD274PDCD1TRPV1PDCD1LG2 | |
| SCHEMBL25530596 | 0.72 | TRPV1 (0.38) | CD274TRPV1PDCD1LG2 | |
| Hydrochloric Acid SCHEMBL620018 | 0.71 | CD274 (0.47) | CD274PDCD1TRPV1PDCD1LG2 | |
| SCHEMBL21451273 | 0.71 | CD274 (0.55) | CD274PDCD1TRPV1PDCD1LG2 | |
| SCHEMBL5049915 | 0.70 | HTR2A (0.41) | CD274TRPV1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387941-A1 | Diphenyl-like Compound, Intermediate Thereof, Preparation Method Therefor, Pharmaceutical Composition Thereof And Uses Thereof | SHANGHAI MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) | 2021-12-16 | — | — | US | disclosed |
| US-11078192-B2 | Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. | 2021-08-03 | — | — | US | disclosed |
| US-20190308957-A1 | AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387941-A1 | Diphenyl-like Compound, Intermediate Thereof, Preparation Method Therefor, Pharmaceutical Composition Thereof And Uses Thereof | CD274, PDCD1LG2, PDCD1 | CD274 1/4885PDCD1 3/4885TRPV1 1514/4885 |
| US-20190308957-A1 | AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PDCD1, CD274, PDCD1LG2 | CD274 2/4885PDCD1 1/4885TRPV1 2231/4885 |
| US-11078192-B2 | Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof | PDCD1, CD274, PDCD1LG2 | CD274 2/4885PDCD1 1/4885TRPV1 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.