Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 5/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10233300 | 0.82 | CD274 (0.48) | TRPV1MBOAT4SQORPDCD1LG2CD274 | |
| Hydrochloric Acid SCHEMBL620018 | 0.81 | CD274 (0.47) | TRPV1MBOAT4SQORPDCD1LG2CD274 | |
| SCHEMBL23398050 | 0.80 | APOBEC3A (0.42) | PDCD1LG2CD274SMN1; SMN2RIPK1ALDH1A1 | |
| SCHEMBL5049915 | 0.79 | HTR2A (0.41) | TRPV1MBOAT4PDCD1LG2CD274 | |
| SCHEMBL14845777 | 0.79 | TRPV1 (0.43) | TRPV1MBOAT4SQORPDCD1LG2CD274 | |
| SCHEMBL15128430 | 0.78 | PDCD1LG2 (0.43) | TRPV1MBOAT4PDCD1LG2CD274SMN1; SMN2 | |
| Anisole SCHEMBL28313547 | 0.73 | CA4 (0.40) | TRPV1PDCD1LG2CD274SMN1; SMN2ALDH1A1 | |
| SCHEMBL18538044 | 0.73 | SQOR (0.39) | TRPV1SQORSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL13624092 | 0.73 | SQOR (0.39) | SQORSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL21451282 | 0.72 | CD274 (0.47) | TRPV1PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | TRPV1 848/4885MBOAT4 1233/4885SQOR 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.