Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966549 | 0.86 | PIK3CG (0.35) | TSHRPIK3CGGRM5GAAPIK3CD | |
| SCHEMBL21452354 | 0.75 | HDAC6 (0.42) | TSHRALOX15GRM5GAANPC1 | |
| SCHEMBL22966630 | 0.75 | PDCD1 (0.41) | — | |
| SCHEMBL12761245 | 0.70 | PDE10A (0.40) | DPP4DPP8DPP9DPP7PDE10A | |
| SCHEMBL15889120 | 0.70 | DPP4 (0.44) | DPP4DPP8DPP9DPP7GRM5 | |
| SCHEMBL13494215 | 0.69 | MAPT (0.49) | DPP4DPP8DPP9DPP7TSHR | |
| SCHEMBL21451962 | 0.67 | RAD52 (0.46) | DPP4DPP8DPP9DPP7PDE10A | |
| SCHEMBL16286092 | 0.66 | RAD52 (0.45) | DPP4DPP8DPP9DPP7PDE10A | |
| SCHEMBL21451964 | 0.65 | RAD52 (0.44) | DPP4DPP8DPP9DPP7GRM5 | |
| SCHEMBL9382117 | 0.65 | GRM5 (0.56) | DPP4DPP8DPP9DPP7PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |