⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL2492247 | 0.77 | — | — | |
| SCHEMBL5178931 | 0.76 | — | — | |
| SCHEMBL4971363 | 0.76 | — | — | |
| SCHEMBL20796 | 0.76 | — | — | |
| SCHEMBL4748477 | 0.76 | ALDH1A1 (0.54) | — | |
| SCHEMBL6726489 | 0.72 | — | — | |
| Methyl Alcohol SCHEMBL897650 | 0.72 | — | — | |
| SCHEMBL17289281 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL49807 | 0.72 | — | — | |
| Water SCHEMBL6169197 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5066 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273135-A1 | PLASMIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2023-11-08 | — | — | EP | claimed |
| CN-116710440-A | Plasmin inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-09-05 | — | — | CN | claimed |
| EP-4038062-A1 | N-(1H-IMIDAZOL-2-YL)BENZAMIDE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT | Kainos Medicine, Inc. (KR) | 2022-08-10 | — | — | EP | claimed |
| CN-114466844-A | N- (1H-imidazol-2-yl) benzamide compounds and pharmaceutical compositions containing the same as active ingredient | 康佳诺医疗科技发展有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-110105377-B | Probe compound for detecting mycobacterium tuberculosis beta-lactamase, preparation method and fluorescent probe | 中国科学院苏州生物医学工程技术研究所 | 2021-08-24 | — | — | CN | claimed |
| WO-2021066559-A1 | N-(1H-IMIDAZOL-2-YL)BENZAMIDE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT | KAINOS MEDICINE, INC. (KR) | 2021-04-08 | — | — | WO | claimed |
| CN-110105377-A | A kind of probe compound, preparation method, a kind of fluorescence probe detecting mycobacterium tuberculosis beta-lactamase | 中国科学院苏州生物医学工程技术研究所 | 2019-08-09 | — | — | CN | claimed |
| US-20170304292-A1 | Tetrahydroisoquinoline Derivatives | UCB BIOPHARMA SPRL (BE) | 2017-10-26 | — | — | US | claimed |
| EP-3204359-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | UCB Biopharma SPRL (BE) | 2017-08-16 | — | — | EP | claimed |
| WO-2016055479-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-04-14 | — | — | WO | claimed |
| US-4343937-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1982-08-10 | — | — | US | claimed |
| US-4342869-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | claimed |
| US-4342757-A | Cephalosporin antibiotic compositions | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | claimed |
| US-4338438-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | claimed |
| US-4338437-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | claimed |
| US-4324890-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1982-04-13 | — | — | US | claimed |
| US-4297488-A | 7-α-Methoxy cephalosporins | MERCK & CO., INC. (US) | 1981-10-27 | — | — | US | claimed |
| US-4292428-A | ANTIBIOTICS; EASILY HYDROLYZED ESTERS AND ETHERS | HOFFMANN-LA ROCHE INC. (US) | 1981-09-29 | — | — | US | claimed |
| US-4211779-A | BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1980-07-08 | — | — | US | claimed |
| US-4198503-A | 3-Carbamoyl substituted-7-ureido substituted cephalosporins | BEECHAM GROUP LIMITED (GB) | 1980-04-15 | — | — | US | claimed |