Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451837 | 0.82 | POLB (0.41) | POLBMAPTLMNATP53GPR6 | |
| SCHEMBL18806194 | 0.80 | ADORA2A (0.37) | POLBMAPTLMNATP53PDCD1 | |
| SCHEMBL18819904 | 0.80 | CDK4 (0.41) | POLBMAPTLMNAPDCD1CD274 | |
| SCHEMBL20249376 | 0.80 | PDCD1 (0.47) | POLBMAPTLMNAPDCD1CD274 | |
| SCHEMBL20255390 | 0.77 | CDK4 (0.43) | POLBMAPTLMNAPDCD1CD274 | |
| SCHEMBL22966559 | 0.77 | CDK4 (0.42) | POLBMAPTLMNATP53CDK4 | |
| SCHEMBL18806181 | 0.77 | CDK4 (0.40) | POLBMAPTLMNAPDCD1CD274 | |
| SCHEMBL20249391 | 0.77 | CDK4 (0.42) | CDK1CDK4CCNB1CCNE1 | |
| SCHEMBL20249522 | 0.77 | CD274 (0.45) | MAPTPDCD1CD274CDK4MEN1 | |
| SCHEMBL18806155 | 0.75 | CDK4 (0.44) | POLBLMNACDK4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |