Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451901 | 0.85 | HDAC4 (0.37) | TNKSTNKS2HDAC4 | |
| SCHEMBL21452484 | 0.83 | HDAC4 (0.36) | HDAC4 | |
| SCHEMBL21452518 | 0.79 | HDAC4 (0.34) | HDAC4 | |
| SCHEMBL21451904 | 0.74 | HDAC4 (0.48) | HDAC4 | |
| SCHEMBL21452489 | 0.73 | TNKS (0.39) | TNKSTNKS2HDAC4 | |
| SCHEMBL21452462 | 0.73 | PDE7A (0.37) | — | |
| SCHEMBL21452501 | 0.72 | PDE7A (0.36) | — | |
| SCHEMBL21452460 | 0.69 | GRIN1 (0.45) | HDAC4 | |
| SCHEMBL23490878 | 0.69 | TNKS (0.32) | TNKSTNKS2HDAC4 | |
| SCHEMBL21452189 | 0.68 | SLC6A4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192602-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海键合医药科技有限公司 | 2019-10-10 | — | — | WO | disclosed |