SCHEMBL21453469

SCHEMBL21453469

C1=c2cc3c4c(n(-c5ccccc5)c3cc2=1)C=CCC=C4

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18830912 0.79 L3MBTL1 (0.50) KDM4EATML3MBTL1
SCHEMBL25951038 0.75 GAA (0.33) KDM4EATML3MBTL1
SCHEMBL22084908 0.71 KDM4E (0.44) KDM4EATML3MBTL1
SCHEMBL21557130 0.71 KDM4E (0.39) KDM4EATML3MBTL1
SCHEMBL25951344 0.70 KDM4E (0.36) KDM4E
SCHEMBL18944591 0.69 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL18594072 0.69 L3MBTL1 (0.44) KDM4EATML3MBTL1
SCHEMBL19595335 0.69 L3MBTL1 (0.41) KDM4EATML3MBTL1
SCHEMBL24221703 0.68 L3MBTL1 (0.41) KDM4EATML3MBTL1
SCHEMBL23544151 0.65 KDM4E (0.35) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L KDM4E 3723/4885ATM 3337/4885L3MBTL1 3731/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L KDM4E 3723/4885ATM 3337/4885L3MBTL1 3731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.