SCHEMBL21453638

SCHEMBL21453638

c1ccc2c(c1)sc1c(-c3ccc4c(c3)c3cccc5c6cccc7sc8cccc(c9ccccc9n4c53)c8c76)cccc12

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.50
PRKDC P78527 5/20 0.39
PARP14 Q460N5 1/20 0.34
PIK3CD O00329 2/20 0.33
PIK3CB P42338 2/20 0.33
BRD4 O60885 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33
BRDT Q58F21 1/20 0.33
GPR3 P46089 1/20 0.33
LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21453782 0.97 ALOX5 (0.47) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL21454048 0.95 ALOX5 (0.48) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL21453664 0.93 ALOX5 (0.46) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL21453753 0.93 ALOX5 (0.54) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL19541036 0.93 ALOX5 (0.54) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL21453625 0.92 ALOX5 (0.46) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL21454262 0.91 ALOX5 (0.44) ALOX5PRKDCPARP14
SCHEMBL16621705 0.91 ALOX5 (0.52) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL16621720 0.91 ALOX5 (0.52) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL16621682 0.90 ALOX5 (0.54) ALOX5PRKDCPARP14PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L ALOX5 1012/4885PRKDC 4258/4885PARP14 1921/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L ALOX5 1012/4885PRKDC 4258/4885PARP14 1921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.