SCHEMBL21454045

SCHEMBL21454045

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)cc4c5ccccc5c5ccccc5c5ccccc5n3c42)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 4/20 0.45
DNM1 Q05193 1/20 0.38
NPY5R Q15761 2/20 0.36
PLA2G2A P14555 1/20 0.36
PLA2G4A P47712 1/20 0.36
NR4A2 P43354 2/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
KDM4E B2RXH2 4/20 0.35
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HSP90AA1 P07900 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16621740 0.98 TSPO (0.46) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL16621693 0.98 TSPO (0.46) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL29442042 0.98 TSPO (0.46) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL24794463 0.98 TSPO (0.46) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL16621683 0.98 TSPO (0.46) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL23138557 0.98 TSPO (0.46) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL23823892 0.95 TSPO (0.44) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL23813964 0.95 TSPO (0.44) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL16621673 0.95 TSPO (0.44) TSPODNM1NPY5RPLA2G2APLA2G4A
SCHEMBL15460105 0.95 TSPO (0.44) TSPODNM1NPY5RPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L TSPO 136/4885DNM1 1709/4885NPY5R 3583/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L TSPO 136/4885DNM1 1709/4885NPY5R 3583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.