SCHEMBL21454095

SCHEMBL21454095

c1ccc(-c2ccc(-n3c4ccccc4c4ccc5c6cccc7c8ccccc8c8ccccc8c8ccccc8n(c76)c5c43)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
HDAC4 P56524 1/20 0.39
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HTT P42858 2/20 0.36
IL1R1 P14778 1/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
PTPN1 P18031 2/20 0.34
MAPK8 P45983 1/20 0.33
MAPK9 P45984 1/20 0.33
DUSP3 P51452 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
FTO Q9C0B1 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21453594 0.91 KDM4E (0.57) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22003585 0.89 L3MBTL1 (0.57) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL10112707 0.89 L3MBTL1 (0.57) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL25479773 0.89 KDM4E (0.41) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL17245347 0.87 L3MBTL1 (0.61) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL18593810 0.87 L3MBTL1 (0.61) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL12691156 0.87 L3MBTL1 (0.61) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL19863523 0.87 L3MBTL1 (0.61) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL21453648 0.87 KDM4E (0.37) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL21454100 0.86 KDM4E (0.45) KDM4EL3MBTL1ATMHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L KDM4E 3723/4885L3MBTL1 3731/4885ATM 3337/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L KDM4E 3723/4885L3MBTL1 3731/4885ATM 3337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.