Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18775641 | 0.75 | NPC1 (0.44) | NPC1CA1CA2HPGD | |
| SCHEMBL18775629 | 0.72 | NPC1 (0.41) | NPC1CA1CA2 | |
| Carbon Monoxide SCHEMBL3455542 | 0.70 | NPC1 (0.40) | NPC1CA1CA2 | |
| SCHEMBL8116098 | 0.70 | NPC1 (0.47) | NPC1CA2HPGD | |
| SCHEMBL6377426 | 0.70 | NPC1 (0.61) | NPC1CA1CA2HPGD | |
| SCHEMBL6376493 | 0.70 | NPC1 (0.61) | NPC1CA1CA2HPGD | |
| SCHEMBL6383859 | 0.70 | NPC1 (0.61) | NPC1CA1CA2HPGD | |
| SCHEMBL10357183 | 0.70 | NPC1 (0.61) | NPC1CA1CA2HPGD | |
| SCHEMBL6379525 | 0.70 | NPC1 (0.61) | NPC1CA1CA2HPGD | |
| SCHEMBL6689341 | 0.68 | NPC1 (0.45) | NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210346866-A1 | Functionalised Chromatography Medium Comprising Polymer Nanofibres and Process of Preparation Thereof | CYTIVA BIOPROCESS R&D AB (SE) | 2021-11-11 | — | — | US | disclosed |
| US-20210060527-A1 | Chromatography Media and Methods for Producing Them | CYTIVA BIOPROCESS R&D AB (SE) | 2021-03-04 | — | — | US | disclosed |
| US-20200238254-A1 | FUNCTIONALIZED HIGH-DENSITY CHROMATOGRAPHY MATRIX, PREPARATION METHOD AND APPLICATION THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2020-07-30 | — | — | US | disclosed |
| US-20190308169-A1 | Functionalised Chromatography Medium Comprising Polymer Nanofibres and Process of Preparation Thereof | CYTIVA BIOPROCESS R&D AB (SE) | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190308169-A1 | Functionalised Chromatography Medium Comprising Polymer Nanofibres and Process of Preparation Thereof | C9, C1R, F3 | NPC1 3650/4885CA1 726/4885CA2 2840/4885 |
| US-20210346866-A1 | Functionalised Chromatography Medium Comprising Polymer Nanofibres and Process of Preparation Thereof | NEFM, SGMS1, FIBP | NPC1 3591/4885CA1 4586/4885CA2 4795/4885 |
| US-20200238254-A1 | FUNCTIONALIZED HIGH-DENSITY CHROMATOGRAPHY MATRIX, PREPARATION METHOD AND APPLICATION THEREOF | HPSE, CD44, HAAO | NPC1 4744/4885CA1 1603/4885CA2 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.