SCHEMBL18775641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18775629	0.98	NPC1 (0.41)	NPC1CA1CA2NAAACYP2C19
	SCHEMBL11572946	0.86	NPC1 (0.40)	NPC1CA1CA2NAAAEPHX1
	SCHEMBL23143077	0.78	CA1 (0.41)	NPC1CA1CA2NAAAEPHX1
	SCHEMBL29020734	0.77	APP (0.39)	CYP2C19PTGS1PDE4ALMNASLC6A6
	SCHEMBL18232617	0.76	EPHX1 (0.39)	CA1CA2NAAAEPHX1CYP2C19
	SCHEMBL24452986	0.76	TSHR (0.38)	LMNAALDH1A1
	SCHEMBL21454778	0.75	NPC1 (0.40)	NPC1CA1CA2HPGD
	Carbon Monoxide SCHEMBL3455542	0.75	NPC1 (0.40)	NPC1CA1CA2
	SCHEMBL6377426	0.74	NPC1 (0.61)	NPC1CA1CA2NAAAEPHX1
	SCHEMBL10357183	0.74	NPC1 (0.61)	NPC1CA1CA2NAAAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.