Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 18/20 | 0.81 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437362 | 1.00 | STING1 (0.81) | STING1SCDTUBB4ATUBBTUBA3C | |
| SCHEMBL21437296 | 0.90 | STING1 (1.00) | STING1SCD | |
| SCHEMBL21437297 | 0.90 | STING1 (1.00) | STING1SCD | |
| SCHEMBL25855526 | 0.90 | STING1 (0.83) | STING1SCDTUBB4ATUBBTUBA3C | |
| SCHEMBL21405853 | 0.81 | STING1 (0.62) | STING1SCDTUBB4ATUBBTUBA3C | |
| SCHEMBL21454830 | 0.80 | STING1 (0.65) | STING1SCDTUBB4ATUBBTUBA3C | |
| SCHEMBL25855520 | 0.80 | STING1 (0.67) | STING1 | |
| SCHEMBL21436989 | 0.80 | STING1 (0.82) | STING1 | |
| SCHEMBL21405767 | 0.79 | STING1 (0.80) | STING1 | |
| SCHEMBL20022277 | 0.79 | STING1 (0.80) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702430-B2 | Aza-benzothiophene compounds as STING agonists | MERCK SHARP & DOHME LLC (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702430-B2 | Aza-benzothiophene compounds as STING agonists | MERCK SHARP & DOHME LLC (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702430-B2 | Aza-benzothiophene compounds as STING agonists | MERCK SHARP & DOHME LLC (US) | 2023-07-18 | — | — | US | disclosed |
| US-20210009608-A1 | AZA-BENZOTHIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2021-01-14 | — | — | US | disclosed |
| WO-2019195063-A1 | AZA-BENZOTHIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702430-B2 | Aza-benzothiophene compounds as STING agonists | STING1, IRF3, CGAS | STING1 1/4885SCD 4776/4885TUBB4A 2725/4885 |
| US-20210009608-A1 | AZA-BENZOTHIOPHENE COMPOUNDS AS STING AGONISTS | STING1, IRF3, CGAS | STING1 1/4885SCD 4776/4885TUBB4A 2725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.