Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455769 | 0.84 | TBXAS1 (0.40) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL21455376 | 0.78 | TBXAS1 (0.39) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL23656748 | 0.77 | MEN1 (0.34) | TBXAS1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL7888801 | 0.76 | TBXAS1 (0.49) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL21455361 | 0.76 | TBXAS1 (0.45) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL23229152 | 0.76 | TBXAS1 (0.45) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL21455732 | 0.75 | TBXAS1 (0.42) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL25899705 | 0.75 | TBXAS1 (0.42) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL23229153 | 0.75 | TBXAS1 (0.48) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL909198 | 0.75 | TBXAS1 (0.48) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |