Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838023 | 1.00 | MTNR1A (0.43) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL22973543 | 0.96 | MTNR1A (0.46) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL21456201 | 0.96 | MTNR1A (0.46) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL29838052 | 0.96 | MTNR1A (0.46) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL21439783 | 0.92 | KMT2A (0.44) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL21456381 | 0.91 | FFAR1 (0.46) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL29556550 | 0.91 | MTNR1A (0.43) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL21455853 | 0.91 | MTNR1A (0.43) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL21456368 | 0.88 | POLB (0.42) | MTNR1AMTNR1BPOLBKDM4ELMNA | |
| SCHEMBL21455854 | 0.88 | KDM4E (0.44) | MTNR1AMTNR1BPOLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778609-B1 | PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | FUJIFILM CORP (JP) | 2022-01-26 | — | — | EP | disclosed |
| EP-3778609-A1 | NOVEL PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | FUJIFILM Corporation (JP) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019194306-A1 | NOVEL PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | 富士フイルム株式会社 | 2019-10-10 | — | — | WO | disclosed |