Mannitol

Mannitol

SCHEMBL21456852

C=CC(=O)O.OCC(O)C(O)C(O)C(O)CO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.56
LMNA P02545 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
TDP1 Q9NUW8 1/20 0.52
USP2 O75604 1/20 0.52
SLCO1B1 Q9Y6L6 1/20 0.52
KDM4E B2RXH2 2/20 0.39
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
OR51E2 Q9H255 1/20 0.36
TOP1 P11387 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
AKR1B1 P15121 1/20 0.31
TSHR P16473 2/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbitol SCHEMBL29824981 1.00 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Sorbitol SCHEMBL29391730 1.00 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Sorbitol SCHEMBL29356940 1.00 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Sorbitol SCHEMBL29358497 1.00 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Xylitol SCHEMBL29733160 0.95 LMNA (0.50) PDE4ALMNAL3MBTL1TDP1USP2
Adonitol SCHEMBL27768098 0.95 LMNA (0.50) PDE4ALMNAL3MBTL1TDP1USP2
E968 SCHEMBL3621953 0.90 LMNA (0.56) PDE4ALMNAL3MBTL1TDP1USP2
E968 SCHEMBL31043056 0.90 LMNA (0.56) PDE4ALMNAL3MBTL1TDP1USP2
E968 SCHEMBL21625759 0.90 LMNA (0.56) PDE4ALMNAL3MBTL1TDP1USP2
E968 SCHEMBL3479791 0.90 LMNA (0.56) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106749960-B Polycarboxylic acid super-plasticizer and its preparation method and application with diesis core configuration 中科院广州化学有限公司南雄材料生产基地 2019-07-02 CN claimed
CN-106749960-A Polycarboxylic acid super-plasticizer and its preparation method and application with diesis core configuration 中科院广州化学有限公司南雄材料生产基地 2017-05-31 CN claimed
CN-101677957-A Polymer formulations for delivery of bioactive agents CARBYLAN BIOSURGERY INC 2010-03-24 CN claimed
CN-122075806-A Coating for medical devices 2026-05-26 CN disclosed
US-20240099866-A1 Coated Medical Devices PHENOX GMBH (DE) 2024-03-28 US disclosed
EP-4288125-A1 COATED MEDICINAL PRODUCT AND METHOD FOR COATING A MEDICINAL PRODUCT Phenox GmbH (DE) 2023-12-13 EP disclosed
EP-4284309-A1 COATED MEDICAL DEVICES Phenox GmbH (DE) 2023-12-06 EP disclosed
CN-116940391-A Coated medical product and method of coating a medical product 菲诺克斯有限公司 2023-10-24 CN disclosed
CN-116916859-A Coated medical device 菲诺克斯有限公司 2023-10-20 CN disclosed
US-11779686-B2 Coating for medical devices PHENOX GMBH (DE) 2023-10-10 US disclosed
US-20200215238-A1 COATING FOR MEDICAL DEVICES PHENOX GMBH (DE) 2020-07-09 US disclosed
EP-3551242-A1 COATING FOR MEDICINAL PRODUCTS Phenox GmbH (DE) 2019-10-16 EP disclosed
CN-106749960-B Polycarboxylic acid super-plasticizer and its preparation method and application with diesis core configuration 中科院广州化学有限公司南雄材料生产基地 2019-07-02 CN disclosed
CN-105567260-B Functionalized photoreactive compounds 罗利克有限公司 2018-09-11 CN disclosed
CN-106749960-A Polycarboxylic acid super-plasticizer and its preparation method and application with diesis core configuration 中科院广州化学有限公司南雄材料生产基地 2017-05-31 CN disclosed
CN-103153952-B The oxime ester derivative of benzo carbazole compound and in photopolymerisable compositions as the purposes of photoinitiator 巴斯夫欧洲公司 2016-07-13 CN disclosed
CN-105567260-A Print Functionalized photoreactive compounds ROLIC AG 2016-05-11 CN disclosed
CN-101268168-B Functionalized photoreactive compounds ROLIC AG (CH) 2016-01-20 CN disclosed
CN-102573941-B Modified hyaluronic acid polymer compositions and related methods CARBYLAN BIOSURGERY, INC. (US) 2014-10-29 CN disclosed
CN-101677957-A Polymer formulations for delivery of bioactive agents CARBYLAN BIOSURGERY INC 2010-03-24 CN disclosed