Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOCK5 | Q9H7D0 | 8/20 | 1.00 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21456947 | 1.00 | DOCK5 (1.00) | DOCK5CCR3SIGMAR1CHRM2CHRM3 | |
| SCHEMBL21481081 | 0.93 | DOCK5 (0.87) | DOCK5SIGMAR1 | |
| SCHEMBL21456939 | 0.93 | DOCK5 (0.87) | DOCK5SIGMAR1 | |
| SCHEMBL21456937 | 0.93 | DOCK5 (0.87) | DOCK5SIGMAR1 | |
| SCHEMBL21475461 | 0.90 | DOCK5 (0.82) | DOCK5SIGMAR1CXCR3 | |
| SCHEMBL21481076 | 0.89 | DOCK5 (1.00) | DOCK5SIGMAR1CHRM2CHRM3 | |
| SCHEMBL21475552 | 0.89 | DOCK5 (1.00) | DOCK5SIGMAR1CHRM2CHRM3 | |
| SCHEMBL21456953 | 0.89 | DOCK5 (1.00) | DOCK5SIGMAR1CXCR3DRD4CACNA1G | |
| SCHEMBL21456951 | 0.89 | DOCK5 (1.00) | DOCK5SIGMAR1CXCR3DRD4CACNA1G | |
| SCHEMBL21480987 | 0.89 | DOCK5 (0.92) | DOCK5SIGMAR1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197659-A1 | NEW INHIBITORS OF BONE RESORPTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-10-17 | — | — | WO | disclosed |
| EP-3553061-A1 | NEW INHIBITORS OF BONE RESORPTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-10-16 | — | — | EP | disclosed |