SCHEMBL21457136

SCHEMBL21457136

CCOc1ccccc1C=C(C#N)C#N

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.70
▸ ALDH1A1 P00352 6/20 0.70
▸ KDM4E B2RXH2 5/20 0.70
▸ KMT2A Q03164 8/20 0.65
▸ MEN1 O00255 5/20 0.65
▸ CYP1A2 P05177 1/20 0.65
▸ CYP2C9 P11712 1/20 0.65
▸ LMNA P02545 6/20 0.60
▸ HTT P42858 1/20 0.60
▸ TRPA1 O75762 1/20 0.50
▸ RAB9A P51151 2/20 0.49
▸ NPC1 O15118 1/20 0.49
▸ PKM P14618 1/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ ATM Q13315 1/20 0.43
▸ HPGD P15428 1/20 0.41
▸ RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1532464 0.81 KDM4E (0.64) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL9789045 0.80 KDM4E (0.78) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL9789047 0.80 KDM4E (0.78) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL14197996 0.79 MEN1 (0.55) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL21457611 0.78 KMT2A (0.74) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL21457613 0.78 KMT2A (0.74) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL9753254 0.78 KMT2A (0.74) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL9753251 0.78 KMT2A (0.74) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL21457624 0.75 KDM4E (0.69) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL21457383 0.75 KDM4E (0.69) MAPTALDH1A1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 — — EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 — — US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 — — CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 — — US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 — — EP disclosed
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