SCHEMBL21457392

SCHEMBL21457392

N#CC(=Cc1ccc(O)cc1O)C(=O)O

nearest known ligand 0.79

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGFR P00533 5/20 0.79
MIF P14174 1/20 0.62
KDM4E B2RXH2 3/20 0.62
SLC16A3 O15427 3/20 0.62
SLC16A1 P53985 3/20 0.62
CISD1 Q9NZ45 1/20 0.62
ALDH1A1 P00352 1/20 0.62
CYP3A4 P08684 1/20 0.62
HPGD P15428 1/20 0.62
GPR35 Q9HC97 1/20 0.62
LCK P06239 1/20 0.58
LMNA P02545 1/20 0.49
PKM P14618 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457390 1.00 EGFR (0.79) EGFRMIFKDM4ESLC16A3SLC16A1
SCHEMBL8749032 0.88 EGFR (1.00) EGFRMIFKDM4ESLC16A3SLC16A1
SCHEMBL8743707 0.88 EGFR (1.00) EGFRMIFKDM4ESLC16A3SLC16A1
SCHEMBL10560029 0.85 EGFR (0.68) EGFRMIFKDM4ESLC16A3SLC16A1
SCHEMBL15988462 0.85 EGFR (0.68) EGFRMIFKDM4ESLC16A3SLC16A1
SCHEMBL23605194 0.83 EGFR (0.60) EGFRMIFKDM4ESLC16A3SLC16A1
SCHEMBL17831051 0.82 KDM4E (0.68) EGFRMIFKDM4ESLC16A3SLC16A1
SCHEMBL29119411 0.81 MIF (0.72) EGFRMIFKDM4EALDH1A1CYP3A4
SCHEMBL2058767 0.81 EGFR (0.66) EGFRKDM4ESLC16A3SLC16A1CISD1
SCHEMBL393439 0.81 EGFR (0.66) EGFRKDM4ESLC16A3SLC16A1CISD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed