SCHEMBL21457670

SCHEMBL21457670

N#CC(=Cc1cccc(O)c1O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EGFR P00533 4/20 0.58
KDM4E B2RXH2 3/20 0.55
LMNA P02545 1/20 0.55
PKM P14618 1/20 0.55
KMT2A Q03164 1/20 0.55
CISD1 Q9NZ45 1/20 0.51
SLC16A3 O15427 1/20 0.51
ALDH1A1 P00352 1/20 0.51
CYP3A4 P08684 1/20 0.51
HPGD P15428 1/20 0.51
SLC16A1 P53985 1/20 0.51
GPR35 Q9HC97 1/20 0.51
ADORA2A P29274 1/20 0.50
ADORA2B P29275 1/20 0.50
ADORA1 P30542 1/20 0.50
ERN1 O75460 1/20 0.47
SENP1 Q9P0U3 1/20 0.47
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457666 1.00 EGFR (0.58) EGFRKDM4ELMNAPKMKMT2A
SCHEMBL393439 0.86 EGFR (0.66) EGFRKDM4ELMNAPKMKMT2A
SCHEMBL2058767 0.86 EGFR (0.66) EGFRKDM4ELMNAPKMKMT2A
SCHEMBL19895348 0.85 EGFR (0.59) EGFRKDM4ELMNAKMT2AALDH1A1
SCHEMBL8743681 0.85 EGFR (0.59) EGFRKDM4ELMNAKMT2AALDH1A1
SCHEMBL30665832 0.84 EGFR (0.55) EGFRKDM4ELMNAPKMKMT2A
SCHEMBL21457354 0.81 ADORA2A (0.75) KDM4ELMNAPKMKMT2AALDH1A1
SCHEMBL21457357 0.81 ADORA2A (0.75) KDM4ELMNAPKMKMT2AALDH1A1
Phosphoric Acid SCHEMBL5329785 0.81 EGFR (0.59) EGFRKDM4ELMNAPKMKMT2A
SCHEMBL21457337 0.79 ALDH1A1 (0.57) KDM4ELMNAPKMKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed