SCHEMBL21457701

SCHEMBL21457701

CCOC(=O)/C(C#N)=C/c1ccc(CC)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.71
MAPT P10636 7/20 0.71
KDM4E B2RXH2 4/20 0.71
HTT P42858 2/20 0.64
PKM P14618 1/20 0.64
KMT2A Q03164 7/20 0.63
MEN1 O00255 4/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
NPC1 O15118 1/20 0.63
MAPK1 P28482 1/20 0.63
CASP3 P42574 1/20 0.63
RAB9A P51151 1/20 0.63
SENP8 Q96LD8 1/20 0.63
SENP7 Q9BQF6 1/20 0.63
SENP6 Q9GZR1 1/20 0.63
PDCD1 Q15116 1/20 0.60
CD274 Q9NZQ7 1/20 0.60
CRHBP P24387 1/20 0.60
CRHR2 Q13324 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457704 1.00 ALDH1A1 (0.71) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL4317761 0.92 ALDH1A1 (0.81) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL2139678 0.92 ALDH1A1 (0.81) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL2139676 0.92 ALDH1A1 (0.81) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL12677356 0.90 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL21457744 0.89 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL21457747 0.89 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL8999255 0.89 ALDH1A1 (0.67) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL9789084 0.89 ALDH1A1 (0.67) ALDH1A1MAPTKDM4EHTTPKM
SCHEMBL8999262 0.89 ALDH1A1 (0.67) ALDH1A1MAPTKDM4EHTTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
CN-110248971-A Copolymer and the optical film for using the copolymer 东曹株式会社 2019-09-17 CN disclosed