SCHEMBL21457750

SCHEMBL21457750

CCCOC(=O)/C(C#N)=C/c1cccc(OCC)c1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.60
PDCD1 Q15116 1/20 0.60
CD274 Q9NZQ7 1/20 0.60
ALDH1A1 P00352 8/20 0.56
KDM4E B2RXH2 4/20 0.56
KMT2A Q03164 3/20 0.56
LMNA P02545 1/20 0.56
DNM1 Q05193 3/20 0.52
HTT P42858 2/20 0.51
PKM P14618 1/20 0.51
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.48
MAPK1 P28482 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ATM Q13315 1/20 0.47
PTP4A1 Q93096 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457753 1.00 MAPT (0.60) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457724 0.91 MAPT (0.71) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457721 0.91 MAPT (0.71) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457737 0.89 MAPT (0.58) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457734 0.89 MAPT (0.58) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457694 0.86 MAPT (0.57) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457691 0.86 MAPT (0.57) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457619 0.86 MAPT (0.58) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457623 0.86 MAPT (0.58) MAPTPDCD1CD274ALDH1A1KDM4E
SCHEMBL21457596 0.85 KDM4E (0.62) MAPTPDCD1CD274ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed