SCHEMBL21457764

SCHEMBL21457764

CCOC(=O)C=C(C#N)c1ccc(OCC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.47
ALDH1A1 P00352 2/20 0.46
NPC1 O15118 3/20 0.45
PLK1 P53350 1/20 0.45
GAA P10253 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
MAOB P27338 2/20 0.44
PLA2G4B P0C869 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RAB9A P51151 2/20 0.42
BRAF P15056 1/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
SCN1A P35498 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
MAOA P21397 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457468 0.89 NQO2 (0.50) ALDH1A1NPC1GAASMN1; SMN2KMT2A
SCHEMBL21457155 0.89 PLK1 (0.49) PARP10ALDH1A1NPC1PLK1GAA
SCHEMBL23866739 0.89 NQO2 (0.50) ALDH1A1NPC1GAASMN1; SMN2KMT2A
SCHEMBL21457731 0.88 NPSR1 (0.45) PARP10ALDH1A1NPC1PLK1GAA
SCHEMBL21457681 0.87 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2KMT2ARAB9AMAPT
SCHEMBL10974068 0.87 SMN1; SMN2 (0.47) ALDH1A1NPC1GAASMN1; SMN2KMT2A
SCHEMBL21457549 0.86 PARP10 (0.45) PARP10ALDH1A1NPC1PLK1GAA
SCHEMBL21457569 0.85 SMN1; SMN2 (0.49) ALDH1A1SMN1; SMN2PLA2G4BKMT2ANPSR1
SCHEMBL21457257 0.85 ESR1 (0.51) ALDH1A1SMN1; SMN2NPSR1LMNACYP1A2
SCHEMBL23866743 0.84 KMT2A (0.46) ALDH1A1GAASMN1; SMN2MAOBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed