Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19407510 | 1.00 | MEN1 (0.70) | MEN1KMT2APKMGAARECQL | |
| SCHEMBL19407437 | 0.87 | MEN1 (0.52) | MEN1KMT2APKMGAARECQL | |
| SCHEMBL19407452 | 0.85 | MEN1 (0.49) | MEN1KMT2AGAARORC | |
| SCHEMBL21458992 | 0.85 | MEN1 (0.49) | MEN1KMT2AGAARORC | |
| SCHEMBL21459121 | 0.82 | MEN1 (0.51) | MEN1KMT2AGAATSHRMAPT | |
| SCHEMBL19407450 | 0.79 | GAA (0.47) | MEN1KMT2AGAATSHRMAPT | |
| SCHEMBL19385974 | 0.78 | MEN1 (0.48) | MEN1KMT2APKMGAATSHR | |
| SCHEMBL19407543 | 0.76 | HDAC1 (0.54) | MEN1KMT2AGAATSHRMAPT | |
| SCHEMBL15480437 | 0.76 | MEN1 (0.67) | MEN1KMT2AGAATSHRHDAC8 | |
| SCHEMBL21459153 | 0.74 | MEN1 (0.46) | MEN1KMT2ATSHRRORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563045-B | Pd (II) -catalysed enantioselective beta-methylene C (sp) 3 ) -H bond activation | 斯克里普斯研究学院 | 2022-08-23 | — | — | CN | disclosed |
| US-11186563-B2 | Pd(II)-catalyzed enantioselective β-methylene C(sp3)—H bond activation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-30 | — | — | US | disclosed |
| US-11186563-B2 | Pd(II)-catalyzed enantioselective β-methylene C(sp3)—H bond activation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-30 | — | — | US | disclosed |
| US-20190315710-A1 | Pd(II)-catalyzed Enantioselective Beta-Methylene C(sp3)–H Bond Activation | THE SCRIPPS RESEARCH INSTITUTE | 2019-10-17 | — | — | US | disclosed |
| US-20190315710-A1 | Pd(II)-catalyzed Enantioselective Beta-Methylene C(sp3)–H Bond Activation | THE SCRIPPS RESEARCH INSTITUTE | 2019-10-17 | — | — | US | disclosed |
| CN-109563045-A | Pd (II) -catalyzed enantioselectivity β -methylene C (sp)3) -H bond activation | 斯克里普斯研究学院 | 2019-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315710-A1 | Pd(II)-catalyzed Enantioselective Beta-Methylene C(sp3)–H Bond Activation | POLQ, AP3D1, AP3S1 | MEN1 3613/4885KMT2A 787/4885PKM 1256/4885 |
| US-11186563-B2 | Pd(II)-catalyzed enantioselective β-methylene C(sp3)—H bond activation | POLQ, AP3D1, AP3S1 | MEN1 3604/4885KMT2A 666/4885PKM 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.