Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146181 | 1.00 | HPGD (0.52) | HPGDALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL14256463 | 0.91 | HPGD (0.50) | HPGDALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL14256462 | 0.90 | HPGD (0.53) | HPGDALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL25143794 | 0.89 | HRH3 (0.43) | HPGDALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL25143725 | 0.89 | HRH3 (0.43) | HPGDALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL20746951 | 0.89 | HPGD (0.61) | HPGDALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL19001381 | 0.87 | HPGD (0.64) | HPGDALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL10205143 | 0.85 | HPGD (0.55) | HPGDALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL21037188 | 0.85 | CHRNB2 (0.58) | HPGDALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL27022571 | 0.85 | HPGD (0.41) | HPGDALDH1A1SMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023191408-A1 | COMBINATION THERAPY FOR PREVENTING OR TREATING OBESITY | 주식회사 엘지화학 | 2023-10-05 | — | — | WO | disclosed |
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |