Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609526 | 0.94 | EPHX2 (0.39) | EPHX2ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL610387 | 0.93 | ALDH1A1 (0.50) | EPHX2ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL1437590 | 0.91 | EPHX2 (0.49) | EPHX2ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL2018904 | 0.90 | ALDH1A1 (0.43) | EPHX2ALDH1A1L3MBTL1GAAKMT2A | |
| SCHEMBL26599493 | 0.81 | NOTUM (0.41) | ALDH1A1 | |
| SCHEMBL21640229 | 0.78 | EPHX2 (0.33) | EPHX2LMNA | |
| SCHEMBL1609203 | 0.77 | PIK3CD (0.39) | — | |
| SCHEMBL23779158 | 0.75 | GAA (0.37) | ALDH1A1MAPK1LMNAGAA | |
| SCHEMBL3328327 | 0.74 | KDM4E (0.48) | EPHX2ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL1437900 | 0.74 | SMO (0.37) | EPHX2ALDH1A1MAPK1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |